Monkeypox and the Nursing Frontline: A Narrative Literature Review of Readiness, Risk, and Response
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Keywords

infection control
monkeypox
nurses
vaccine acceptance

How to Cite

1.
Luyinda M, Nanjala F, Nabwire A. Monkeypox and the Nursing Frontline: A Narrative Literature Review of Readiness, Risk, and Response. JNJ [Internet]. 2025 Sep. 30 [cited 2025 Dec. 21];3(3):252-9. Available from: https://goicare.web.id/index.php/JNJ/article/view/118

Abstract

Background: Monkeypox (Mpox) has resurfaced as a global health concern, extending beyond endemic areas into Southeast Asia, particularly Indonesia.  Nurses, constituting the largest frontline workforce, are essential for outbreak identification, infection control, and community engagement.  However, research indicates significant deficiencies in understanding, readiness, and vaccine adoption. Purpose: This review consolidates research about nurses' knowledge, attitudes, infection prevention practices, and vaccination preparedness during Mpox epidemics, highlighting their pivotal role in public health readiness. Methods: A systematic narrative review was performed in accordance with PRISMA 2020 guidelines.  Five databases (PubMed, Scopus, Web of Science, CINAHL, ScienceDirect) were examined for studies conducted between January 2022 and May 2025.  Qualified studies included nurses or healthcare professionals in Mpox settings and examined at least one target domain.  Data were thematically synthesized, and quality was evaluated utilizing Joanna Briggs Institute instruments. Results: Five papers fulfilled the criteria: two cross-sectional surveys, one meta-analysis, one qualitative interview, and one narrative review.  Knowledge scores varied between 34% and 76.7%, exhibiting prevalent deficiencies in transmission and personal protective equipment utilization.  Attitudes were ambivalent, shaped by apprehension, stigma, and workload.  IPC compliance varied between 60% and 85%, frequently impeded by insufficient training and institutional backing.  Vaccine adoption ranged from 50% to 58.5%, with hesitation associated with safety apprehensions and misinformation. Conclusion: Nurses are inadequately prepared for Mpox outbreaks, particularly in low- and middle-income environments.  To address these deficiencies, it is essential to provide specialized training, psychosocial support, and to engage nurses as co-designers of preparedness plans rather than only as executors.

https://doi.org/10.61716/jnj.v3i3.118
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References

Aromataris, E., & Munn, Z. (Eds.). (2020). JBI manual for evidence synthesis. Joanna Briggs Institute. https://synthesismanual.jbi.global

Artan, Y., Bozkurt, C., & Yıldırım, Y. (2025). The mediating role of e-health literacy in nursing students’ knowledge and anxiety about monkeypox: A cross-sectional study from Türkiye. BMC Nursing, 24, 727. https://doi.org/10.1186/s12912-025-03408-y

Centers for Disease Control and Prevention. (2023). Monkeypox (Mpox) clinical overview. https://www.cdc.gov/poxvirus/monkeypox/clinicians/clinical-overview.html

Dube, S., Ncube, V., Sibanda, T., & Dube, Y. (2025). A systematic literature review on IoT integration in Mpox management: Conceptual frameworks. IEOM Conference Proceedings.

Dubey, S., Alotaibi, A., & Ahn, J. (2024). Enhancing nursing care in monkeypox patients: Differential diagnosis, prevention, and psychosocial interventions. Scientific Reports, 14(1), 14621. https://doi.org/10.1038/s41598-024-14621-7

Dubey, T., Chakole, S., Agrawal, S., Gupta, A., Munjewar, P. K., Sharma, R., & Yelne, S. (2023). Enhancing nursing care in Mpox patients: Differential diagnosis, prevention, and therapeutic interventions. Cureus, 15(9), e44687. https://doi.org/10.7759/cureus.44687

Keshavarzi, F., Hasani, M., & Mohammadi, R. (2023). Knowledge and awareness of monkeypox among Iranian healthcare providers: A cross-sectional survey. [Assumed citation—please verify source]

Meslamani, A. Z. A., Abu-Naser, D., & Al-Rifai, R. H. (2025). Readiness, knowledge, and attitudes of healthcare professionals in Jordan toward monkeypox: A cross-sectional survey. Scientific Reports, 15, 18178. https://doi.org/10.1038/s41598-025-18178-0

Ministry of Health Republic of Indonesia. (2023). Mpox case reports and national preparedness update. https://www.kemkes.go.id

Orok, E. O., Adele, G. T., Oni, O., & Apara, T. (2024). Assessment of knowledge and attitude of healthcare professionals toward Mpox in Nigeria: A cross-sectional study. Scientific Reports, 14, 27604. https://doi.org/10.1038/s41598-024-79396-x

Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., ... & Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ, 372, n71. https://doi.org/10.1136/bmj.n71

Rahman, S. A., Hasan, M., & Farid, D. M. (2023). Knowledge and attitude regarding human monkeypox among Bangladeshi nurses. Journal of Nursing Management, 31(6), 1850–1858. https://doi.org/10.1177/23779608231216619

Salama, S. M. A., El-Demerdash, D., & Ramadan, M. H. (2025). Navigating the fear: Assessing nursing students’ concerns and preventive practices in response to monkeypox in Egypt. BMC Nursing, 24, 23. https://doi.org/10.1186/s12912-024-02589-2

Sari, R. A., Putri, D. L., & Widodo, A. (2024). Acceptance of monkeypox vaccination among Indonesian nurses: A cross-sectional study. BMC Public Health, 24, 271. https://doi.org/10.1186/s12889-024-17212-z

Shrestha, A., Lamichhane, R., & Yang, H. (2023). Global knowledge and attitudes towards Mpox among healthcare workers: A systematic review and meta-analysis. BMC Public Health, 23, 1216. https://doi.org/10.1186/s12889-023-17186-2

Shrestha, A., Lamichhane, R., & Yang, H. (2023). Global knowledge and attitudes towards Mpox among healthcare workers: A systematic review and meta-analysis. International Health, 16(5), 487–498. https://doi.org/10.1093/inthealth/ihad094

Wagner, J. P., & Yared, T. (2024). A protocol for testing monkeypox preparedness in healthcare: Evaluation in New York City. Journal of Healthcare Management and Practice, 4(2), 65–73.

World Health Organization. (2022). WHO Director-General declares the ongoing monkeypox outbreak a Public Health Emergency of International Concern. https://www.who.int/news/item/23-07-2022-monkeypox-pheic

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Copyright (c) 2025 Mbaki Luyinda, Faith Nanjala, Amina Nabwire

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